ALNY monthly performance report

Explore ALNY's monthly returns, drawdown, and seasonality trends — updated every month.

ALNY monthly report

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Key takeaways

  • Alnylam Pharmaceuticals (ALNY) closed November 2026 at $165.04, up 0.02% for the month and −63.65% over the trailing 12 months.
  • Year-to-date, ALNY is −58.50%, underperforming the S&P 500 which has returned +10.62% YTD.
  • The stock is trading −40.26% versus its 200-day moving average ($276.26), a cautious technical signal.
  • Over the past three years, ALNY has underperformed the S&P 500 by −71.36%, with a relative strength index reading of 58.4.
  • Win rate over the trailing 39 months stands at 43.6% — 17 positive months versus 22 negative months.

Alnylam Pharmaceuticals ended November 2026 at $165.04, posting a monthly return of +0.02%. The S&P 500 returned −0.18% over the same window, leaving relative performance at +0.20%.

The current quarter stands at −33.11% (Q4 2026 (QTD)), while medium-term trend remains soft: price is −40.26% versus the 200-day moving average ($276.26).

Year-to-date, ALNY is −58.50% against SPY +10.62%, a gap of −69.12%. The stock is currently −65.60% below its 52-week high, with maximum 3-year drawdown at −69.13%.

ALNY trailing returns vs S&P 500
PeriodALNYS&P 500 (SPY)Excess return
1 Day+5.36%−0.36%+5.72%
1 Week+5.84%+2.59%+3.24%
1 Month+0.02%−0.18%+0.20%
3 Months−27.82%−2.37%−25.45%
6 Months−43.38%+0.83%−44.21%
YTD−58.50%+10.62%−69.12%
12 Months−63.65%+12.25%−75.90%
3 Years+0.02%+71.37%−71.36%
ALNY best months
RankMonthReturn
#1Jun 2024+63.71%
#2Jul 2025+20.29%
#3Aug 2026+17.11%
#4May 2025+15.70%
#5Jan 2025+15.30%
ALNY worst months
RankMonthReturn
#1Oct 2026−33.13%
#2Jul 2026−31.73%
#3Jan 2026−14.99%
#4Oct 2023−14.29%
#5Feb 2024−12.62%
ALNY quarterly returns
QuarterReturn
Q3 2025+39.84%
Q4 2025−12.80%
Q1 2026−16.79%
Q2 2026−9.02%
Q3 2026−18.03%
Q4 2026 (QTD)−33.11%
ALNY calendar year returns
YearReturn
2023−19.46%
2024+22.94%
2025+68.99%
2026−58.50%
ALNY drawdown metrics
MetricValue
52-Week High$479.79 (2025-12-03)
52-Week Low$149.18 (2026-11-10)
Current Price$165.04
200-Day Moving Average$276.26
Price vs 200DMA−40.26%
3-Year Maximum Drawdown−69.13% (2026-11-10)
Current Drawdown from 52W High−65.60%
ALNY relative strength vs S&P 500
RS metricValue
RS Index (3-year, rebased to 100)58.4
3-Year Excess Return vs S&P 500−71.36%
RS Peak197.8 (Sep 2025)
RS Trough53.9 (Nov 2026)
StatusUnderperforming Benchmark

Frequently asked questions

What was ALNY's return for this report period?

ALNY returned +0.02% in the latest monthly window ending 2026-11-13.

Has ALNY outperformed SPY year to date?

YTD ALNY: −58.50% vs SPY: +10.62%.

What is ALNY's 12-month return?

−63.65% over the trailing 12 months.

Is ALNY above or below its 200-day moving average?

Price is −40.26% versus 200DMA ($276.26).

What is the maximum drawdown in the 3-year window?

−69.13% on 2026-11-10.