ALNY Quarterly Statistics
ALNY quarterly stock returns with Q1–Q4 history, seasonality patterns, and performance tables for U.S. equity research.
Alnylam Pharmaceuticals, Inc. (ALNY) company overview
Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam's commercial RNAi therapeutic products include Onpattro and Amvuttra (for hATTR amyloidosis), Givlaari (for acute hepatic porphyria), and Oxlumo (for primary hyperoxaluria type 1), all developed and commercialized by Alnylam. Plus, Leqvio (for hypercholesterolemia) and Qfitlia (for hemophilia A or B), which are being commercialized by Alnylam's partners, Novartis and Sanofi, respectively. It also has several clinical programs across various therapeutic areas, including cardio-metabolic diseases, neuroscience, and hematology.
| Period | Return % |
|---|---|
| 2004-Q2 | 8 |
| 2004-Q3 | -17.83 |
| 2004-Q4 | 33.16 |
| 2005-Q1 | -3.3 |
| 2005-Q2 | 0.14 |
| 2005-Q3 | 56.73 |
| 2005-Q4 | 15.03 |
| 2006-Q1 | 35.73 |
| 2006-Q2 | -11.08 |
| 2006-Q3 | -7.15 |
| 2006-Q4 | 51.67 |
| 2007-Q1 | -16.55 |
| 2007-Q2 | -13.3 |
| 2007-Q3 | 107.27 |
| 2007-Q4 | -11.48 |
| 2008-Q1 | -15.63 |
| 2008-Q2 | 7.35 |
| 2008-Q3 | 6.51 |
| 2008-Q4 | -10.79 |
| 2009-Q1 | -24.29 |
| 2009-Q2 | 19.35 |
| 2009-Q3 | 1.25 |
| 2009-Q4 | -18.2 |
| 2010-Q1 | -6.17 |
| 2010-Q2 | -11.7 |
| 2010-Q3 | -18.42 |
| 2010-Q4 | -18.85 |
| 2011-Q1 | -4.5 |
| 2011-Q2 | -3.6 |
| 2011-Q3 | -30.11 |
| 2011-Q4 | 35.83 |
| 2012-Q1 | 27.83 |
| 2012-Q2 | 4.95 |
| 2012-Q3 | 54.91 |
| 2012-Q4 | -3.18 |
| 2013-Q1 | 27.13 |
| 2013-Q2 | 31.75 |
| 2013-Q3 | 94.03 |
| 2013-Q4 | -2.28 |
| 2014-Q1 | 5.14 |
| 2014-Q2 | -6.32 |
| 2014-Q3 | 16.86 |
| 2014-Q4 | 25.94 |
| 2015-Q1 | 6.8 |
| 2015-Q2 | 13.88 |
| 2015-Q3 | -31.65 |
| 2015-Q4 | 18.19 |
| 2016-Q1 | -32.53 |
| 2016-Q2 | -14.35 |
| 2016-Q3 | 10.32 |
| 2016-Q4 | -45.13 |
| 2017-Q1 | 32.63 |
| 2017-Q2 | 58.13 |
| 2017-Q3 | 43.81 |
| 2017-Q4 | 3.88 |
| 2018-Q1 | -9.67 |
| 2018-Q2 | -2.66 |
| 2018-Q3 | -10.77 |
| 2018-Q4 | -17.46 |
| 2019-Q1 | 28.44 |
| 2019-Q2 | -20.98 |
| 2019-Q3 | 11.68 |
| 2019-Q4 | 54.57 |
| 2020-Q1 | -5.86 |
| 2020-Q2 | 41.68 |
| 2020-Q3 | -2.13 |
| 2020-Q4 | -9.58 |
| 2021-Q1 | 10.22 |
| 2021-Q2 | 19.54 |
| 2021-Q3 | 11.23 |
| 2021-Q4 | -11.99 |
| 2022-Q1 | -6.11 |
| 2022-Q2 | -13.85 |
| 2022-Q3 | 35.02 |
| 2022-Q4 | 20.76 |
| 2023-Q1 | -14.24 |
| 2023-Q2 | -5.36 |
| 2023-Q3 | -6.64 |
| 2023-Q4 | 6.96 |
| 2024-Q1 | -23.33 |
| 2024-Q2 | 58.48 |
| 2024-Q3 | 13.03 |
| 2024-Q4 | -14.76 |
| 2025-Q1 | 15.58 |
| 2025-Q2 | 27.5 |
| 2025-Q3 | 41.59 |
| 2025-Q4 | -13.68 |
| 2026-Q1 | -17.32 |
| 2026-Q2 | -8.43 |
| 2026-Q3 | -18.21 |
| 2026-Q4 | 0.65 |
| Period | Return % |
|---|---|
| 2004-06 | 8 |
| 2004-07 | -31.88 |
| 2004-08 | 6.8 |
| 2004-09 | 4.73 |
| 2004-10 | -8.85 |
| 2004-11 | 52.38 |
| 2004-12 | -6.63 |
| 2005-01 | -6.29 |
| 2005-02 | 2.14 |
| 2005-03 | 2.52 |
| 2005-04 | 6.14 |
| 2005-05 | -4.11 |
| 2005-06 | -2.14 |
| 2005-07 | 33.56 |
| 2005-08 | -2.56 |
| 2005-09 | 18.95 |
| 2005-10 | -14.96 |
| 2005-11 | 30.7 |
| 2005-12 | 6.05 |
| 2006-01 | 0.9 |
| 2006-02 | 19.64 |
| 2006-03 | 9.39 |
| 2006-04 | -12.56 |
| 2006-05 | -3.84 |
| 2006-06 | 1.96 |
| 2006-07 | -15.32 |
| 2006-08 | 1.96 |
| 2006-09 | 10.68 |
| 2006-10 | 36.85 |
| 2006-11 | 8.87 |
| 2006-12 | -0.33 |
| 2007-01 | -0.75 |
| 2007-02 | -11.49 |
| 2007-03 | -4.26 |
| 2007-04 | 4.28 |
| 2007-05 | -12.63 |
| 2007-06 | -7.38 |
| 2007-07 | 58.72 |
| 2007-08 | -3.07 |
| 2007-09 | 40.22 |
| 2007-10 | -3.63 |
| 2007-11 | 3.29 |
| 2007-12 | -10.85 |
| 2008-01 | 3.3 |
| 2008-02 | -5.46 |
| 2008-03 | -14.08 |
| 2008-04 | 2.79 |
| 2008-05 | 15.15 |
| 2008-06 | -7.44 |
| 2008-07 | 30.12 |
| 2008-08 | -14.75 |
| 2008-09 | -2.36 |
| 2008-10 | -20.55 |
| 2008-11 | -20.74 |
| 2008-12 | 35.66 |
| 2009-01 | -14.72 |
| 2009-02 | -12.57 |
| 2009-03 | 3.25 |
| 2009-04 | -3.68 |
| 2009-05 | 11.01 |
| 2009-06 | 9.38 |
| 2009-07 | 4.49 |
| 2009-08 | -4.17 |
| 2009-09 | 1.7 |
| 2009-10 | -24.87 |
| 2009-11 | -1.35 |
| 2009-12 | 4.82 |
| 2010-01 | -4.09 |
| 2010-02 | 3.08 |
| 2010-03 | -2.3 |
| 2010-04 | -0.35 |
| 2010-05 | -6.84 |
| 2010-06 | -4.94 |
| 2010-07 | 2.2 |
| 2010-08 | -10.94 |
| 2010-09 | -10.24 |
| 2010-10 | 7.09 |
| 2010-11 | -30.37 |
| 2010-12 | 7.76 |
| 2011-01 | 4.77 |
| 2011-02 | 6.29 |
| 2011-03 | -12.93 |
| 2011-04 | 7.32 |
| 2011-05 | 2.05 |
| 2011-06 | -10.51 |
| 2011-07 | 0.11 |
| 2011-08 | -25.59 |
| 2011-09 | -5.87 |
| 2011-10 | 23.59 |
| 2011-11 | -12.56 |
| 2011-12 | 14.79 |
| 2012-01 | 41.84 |
| 2012-02 | 15.4 |
| 2012-03 | -17.02 |
| 2012-04 | 2.89 |
| 2012-05 | -10.1 |
| 2012-06 | 13.77 |
| 2012-07 | 60.43 |
| 2012-08 | -2.14 |
| 2012-09 | 2.73 |
| 2012-10 | -13.94 |
| 2012-11 | 4.95 |
| 2012-12 | 7.54 |
| 2013-01 | 32.22 |
| 2013-02 | -1.82 |
| 2013-03 | 2.87 |
| 2013-04 | -1.72 |
| 2013-05 | 27.89 |
| 2013-06 | 1.21 |
| 2013-07 | 48.94 |
| 2013-08 | 12.19 |
| 2013-09 | 23.57 |
| 2013-10 | -10 |
| 2013-11 | 6.23 |
| 2013-12 | 5.07 |
| 2014-01 | 30.11 |
| 2014-02 | -2.89 |
| 2014-03 | -17.36 |
| 2014-04 | -26.23 |
| 2014-05 | 19.71 |
| Date | Open | High | Low | Close | Volume |
|---|---|---|---|---|---|
| 2026-10-09 | 224.74 | 232.86 | 222.71 | 232.68 | — |
| 2026-10-08 | 222.05 | 225.9 | 218.39 | 224.53 | — |
| 2026-10-07 | 224.39 | 230.42 | 222.46 | 224.41 | — |
| 2026-10-06 | 221.14 | 229.12 | 217.18 | 223.94 | — |
| 2026-10-05 | 218.36 | 222.08 | 215.53 | 219.89 | — |
| 2026-10-02 | 231.31 | 231.36 | 219.4 | 219.72 | — |
| 2026-10-01 | 248.21 | 251.71 | 230.06 | 231.18 | — |
| 2026-09-30 | 253.68 | 254.44 | 246.66 | 246.74 | — |
| 2026-09-29 | 254.86 | 257.27 | 251.02 | 254.07 | — |
| 2026-09-28 | 256.1 | 256.34 | 248.12 | 255.36 | — |
| 2026-09-25 | 248.39 | 256.66 | 247.51 | 255.96 | — |
| 2026-09-24 | 246.9 | 251.79 | 245.52 | 249.59 | — |
| 2026-09-23 | 251.59 | 253.81 | 245.34 | 246.51 | — |
| 2026-09-21 | 240.37 | 247.1 | 237.97 | 244.32 | — |
| 2026-09-18 | 246.49 | 246.49 | 238.51 | 239.56 | — |
| 2026-09-17 | 242.6 | 245.62 | 239.68 | 245.51 | — |
| 2026-09-16 | 239.5 | 242.24 | 236.27 | 239.36 | — |
| 2026-09-15 | 246.99 | 247.43 | 237.44 | 238.27 | — |
| 2026-09-14 | 250.16 | 252.79 | 244.18 | 249.99 | — |
| 2026-09-11 | 248.05 | 254.08 | 246.01 | 248.68 | — |
| 2026-09-10 | 256.68 | 256.68 | 246.42 | 247.51 | — |
| 2026-09-09 | 256.48 | 261.98 | 253.27 | 258 | — |
| 2026-09-08 | 259.73 | 272.08 | 254.01 | 260.1 | — |
| 2026-09-04 | 258.02 | 266.85 | 258.02 | 266.11 | — |
| 2026-09-02 | 246.48 | 269.94 | 246.48 | 267.4 | — |
| 2026-08-31 | 233.88 | 243.02 | 233.33 | 240.69 | — |
| 2026-08-27 | 236.56 | 238 | 230.46 | 236.56 | — |
| 2026-08-26 | 238.54 | 242.89 | 236.6 | 239 | — |
| 2026-08-25 | 236.56 | 240.67 | 235.41 | 240.08 | — |
| 2026-08-24 | 235.83 | 237.91 | 228.59 | 236.01 | — |
| 2026-08-21 | 228.88 | 238.97 | 228.34 | 236.22 | — |
| 2026-08-20 | 238.97 | 240.88 | 228.74 | 229.3 | — |
| 2026-08-19 | 234.36 | 244 | 233.4 | 242.61 | — |
| 2026-08-18 | 226 | 230.91 | 222.01 | 228.61 | — |
| 2026-08-17 | 225.76 | 227.99 | 222.12 | 224.6 | — |
| 2026-08-14 | 223.52 | 228.98 | 220.23 | 228.65 | — |
| 2026-08-13 | 225.95 | 227.54 | 222.7 | 227.12 | — |
| 2026-08-12 | 219 | 224.66 | 219 | 223.95 | — |
| 2026-08-11 | 217.41 | 223.44 | 216.5 | 221.2 | — |
| 2026-08-10 | 218 | 223.5 | 215.61 | 216.98 | — |
| 2026-08-07 | 217.31 | 219.6 | 210.49 | 219.2 | — |
| 2026-08-06 | 228.58 | 234 | 212.98 | 216.12 | — |
| 2026-08-05 | 221.74 | 229.65 | 221.5 | 228.72 | — |
| 2026-08-04 | 221.47 | 222.59 | 215.1 | 219 | — |
| 2026-08-03 | 208.04 | 220.49 | 208.04 | 220.33 | — |
| 2026-07-31 | 205.46 | 207.99 | 200.11 | 205.52 | — |
| 2026-07-30 | 225.03 | 230 | 197.81 | 205.48 | — |
| 2026-07-29 | 287.84 | 290.6 | 284.15 | 286.62 | — |
| 2026-07-28 | 282.79 | 290.47 | 281.23 | 288.41 | — |
| 2026-07-27 | 274.47 | 284.68 | 272.66 | 278.4 | — |
| 2026-07-24 | 269.4 | 275.53 | 265.64 | 271.77 | — |
| 2026-07-23 | 265.95 | 269.22 | 262.21 | 268.74 | — |
| 2026-07-22 | 270.84 | 272.42 | 264.23 | 266.99 | — |
| 2026-07-21 | 272.4 | 278.3 | 270.01 | 271.37 | — |
| 2026-07-20 | 269.25 | 275.25 | 266.27 | 272.67 | — |
| 2026-07-17 | 280.99 | 284.36 | 266.43 | 267.47 | — |
| 2026-07-16 | 279.64 | 286.6 | 273.78 | 283.15 | — |
| 2026-07-15 | 281.7 | 284.8 | 275.84 | 279.14 | — |
| 2026-07-14 | 283.59 | 286.76 | 279.43 | 281.26 | — |
| 2026-07-13 | 298.76 | 298.76 | 279.41 | 288.06 | — |
| 2026-07-10 | 314.71 | 322.49 | 293.78 | 298.76 | — |
| 2026-07-09 | 378.49 | 380 | 311.1 | 312.79 | — |
| 2026-07-08 | 318.5 | 325.3 | 316.77 | 323.5 | — |
| 2026-07-07 | 316.44 | 321.98 | 315.42 | 321.59 | — |
| 2026-07-06 | 319.34 | 319.34 | 307.13 | 313.04 | — |
| 2026-07-02 | 303.87 | 317.17 | 303 | 312.78 | — |
| 2026-07-01 | 304.54 | 309.27 | 301.5 | 301.67 | — |
| 2026-06-30 | 295.18 | 302.74 | 295.18 | 301.03 | — |
| 2026-06-29 | 295.96 | 298.06 | 291.9 | 293.52 | — |
| 2026-06-26 | 297.57 | 302.96 | 290.37 | 291.37 | — |
| 2026-06-25 | 293.68 | 298.35 | 290.45 | 293.17 | — |
| 2026-06-24 | 290.95 | 303.46 | 288.85 | 294.06 | — |
| 2026-06-23 | 290.89 | 291.95 | 285.26 | 288.18 | — |
| 2026-06-22 | 278.42 | 286.67 | 278.17 | 286.41 | — |
| 2026-06-18 | 282.98 | 282.98 | 273.11 | 278.09 | — |
| 2026-06-17 | 281.31 | 288 | 277.78 | 282.72 | — |
| 2026-06-16 | 288.13 | 288.47 | 276.94 | 281.9 | — |
| 2026-06-15 | 282.92 | 288.07 | 281.36 | 287.8 | — |
| 2026-06-12 | 288.96 | 291.28 | 281.77 | 282.85 | — |
| 2026-06-11 | 290.7 | 292.98 | 285.22 | 289.39 | — |
| 2026-06-10 | 297.69 | 299.7 | 290.54 | 291.22 | — |
| 2026-06-09 | 297.31 | 302.85 | 293.98 | 297.69 | — |
| 2026-06-05 | 304.62 | 306.71 | 300.5 | 303.05 | — |
| 2026-06-04 | 297.22 | 310.53 | 293.85 | 303.64 | — |
| 2026-06-03 | 284.48 | 293.16 | 283.1 | 292.58 | — |
| 2026-06-02 | 293.94 | 295.6 | 285 | 286.12 | — |
| 2026-06-01 | 299.51 | 303.98 | 295.14 | 295.63 | — |
| 2026-05-29 | 302.43 | 305.68 | 297.62 | 301.98 | — |
| 2026-05-28 | 293 | 305.97 | 292.77 | 305.06 | — |
| 2026-05-27 | 293.4 | 299.89 | 292.91 | 295.63 | — |
| 2026-05-22 | 299.12 | 303.33 | 294.99 | 297.45 | — |
| 2026-05-21 | 296.64 | 301.43 | 293 | 300.51 | — |
| 2026-05-20 | 297.8 | 300.08 | 292.1 | 298.48 | — |
| 2026-05-19 | 284.38 | 294.93 | 284.38 | 294.3 | — |
| 2026-05-18 | 287.14 | 291.97 | 285.26 | 286.27 | — |
| 2026-05-15 | 294.78 | 298 | 286.76 | 286.98 | — |
| 2026-05-14 | 290.72 | 297 | 287.51 | 293.45 | — |
| 2026-05-13 | 290.7 | 298.38 | 288.56 | 291.48 | — |
| 2026-05-12 | 288.66 | 295.86 | 286.73 | 292.03 | — |
| 2026-05-11 | 294.15 | 296.37 | 284.28 | 284.84 | — |
| 2026-05-08 | 295.95 | 300.17 | 293.06 | 295.05 | — |
| 2026-05-07 | 300.55 | 303.46 | 293.78 | 295.91 | — |
| 2026-05-06 | 301.58 | 306.03 | 298.96 | 303 | — |
| 2026-05-05 | 297.81 | 302.67 | 295.02 | 301.11 | — |
| 2026-05-04 | 298 | 300.49 | 288.05 | 297.92 | — |
| 2026-05-01 | 308.85 | 311.88 | 295.79 | 296.11 | — |
| 2026-04-30 | 307.48 | 317.55 | 287 | 309.49 | — |
| 2026-04-29 | 300.51 | 304.22 | 294.06 | 301.19 | — |
| 2026-04-28 | 308.97 | 314.17 | 301.8 | 302.11 | — |
| 2026-04-27 | 303.87 | 314.65 | 303.87 | 308.51 | — |
| 2026-04-24 | 309.91 | 311.1 | 302.9 | 305.54 | — |
| 2026-04-23 | 313.59 | 315.83 | 310.79 | 313.79 | — |
| 2026-04-22 | 308.46 | 312.69 | 307.85 | 310.58 | — |
| 2026-04-21 | 307.32 | 310.49 | 301.63 | 308.43 | — |
| 2026-04-20 | 306.56 | 312.25 | 305.21 | 310.94 | — |
| 2026-04-17 | 326.09 | 326.53 | 306.04 | 309.66 | — |
| 2026-04-16 | 333.39 | 333.39 | 318.93 | 320.13 | — |
| 2026-04-15 | 342 | 342.23 | 331.02 | 333.39 | — |
| 2026-04-14 | 330.81 | 343.36 | 330.81 | 339.41 | — |
| 2026-04-13 | 320.66 | 333.55 | 318.99 | 333 | — |